Ann (Carole Lombard) and David Smith (Robert Montgomery) are a happily married couple living in New York. One morning, Ann asks David if he had to do it over again, would he marry her? To her shock, he answers “no”, he wouldn't. Later that day, they both separately find out that, due to a complication when they married three years ago, they are in fact not legally married. Ann does not mention this to David, and thinks he will remarry her that very night after he takes her out to a romantic dinner. When this does not happen, she angrily kicks David out of their home.

David spends the night at his club, where a friend advises him to just wait a day, and then come back home. But when David drops by after work, Ann announces behind a closed door that she is not married to David, and has no intention of ever marrying him.

An angry and disheartened David takes to following Ann around, in the process interrupting a date and getting her fired from her job. A friend and co-worker of David, Jeff (Gene Raymond), tells David he will talk to Ann and persuade her to remarry David. But when David shows up later that evening, he finds that Jeff has instead arranged a date with Ann the following night. David arranges a blind date at the same restaurant, but his date is vulgar and rude and the affair ends in disaster.

Later, Ann and Jeff go to the World's Fair, but become stuck on a ride and are forced to sit through several hours of rain many feet up in the air.

Ann and Jeff begin to date seriously, and Ann even meets Jeff's parents, an event that quickly becomes awkward when David barges in. To escape, Ann and Jeff decide to take a vacation with Jeff's parents at a skiing resort – the same resort where Ann and David had earlier been planning to holiday. Upon arriving at the resort, they find that David has rented a cabin right next to them, but when confronted, David simply faints. David spends the next few hours pretending to be sick and delirious whilst Ann fawns over him, but when Ann discovers his deception, she yells at him and leaves. Ann then loudly stages a pretend one-way conversation with Jeff in order for David to see they are very serious about each other. This falls through when David storms in to find her talking to thin air. In the end, Ann and David, once the picture of a happy couple, are screaming bloody murder at each other when Jeff walks in.

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“Mr. and Mrs. Smith” is a well-produced and expertly directed screen comedy. Carole Lombard and Robert Montgomery are perfectly matched and if one didn't pay too close attention to the credits, they might never suspect that Alfred Hitchcock was the director.

Before Hollywood had entirely typecast Hitchcock as the master of suspense, with “Mr. & Mrs. Smith” he was allowed to fashion an elegant romantic trifle with Robert Montgomery and Carole Lombard. It probably won't replace “Rear Window” or “Psycho” in your affections, but the film is more than a curious footnote to the director's career. While Hitchcock later claimed he directed the film – the only pure comedy he made in America – as a favor to Lombard, the files at RKO Radio Pictures show that Hitchcock himself pursued the project. Cary Grant was the first choice of both Hitchcock and Lombard. His schedule, however, was booked and they had to settle on Montgomery instead. A good time was had by all during the shoot - Lombard directed Hitchcock's notorious cameo, making the flustered director re-do the simple scene over and over, much to the amusement of the crew.

Carole Lombard's career as one of the silver screen's great leading ladies was tragically short because of her untimely death in a plane crash at age 33 (she was returning to Hollywood from a war bond rally in her native Indiana). Possessed of glamorous good looks and a lithe and graceful build (athletic, too--as a tomboy preteen, she regularly brawled with her older brothers), Lombard's great talent was for comedy, specifically the screwball variety that dominated the mid-1930s, with its wordplay and wit-matching, its glitzy surroundings and ditzy characters. Smart, funny and sexy--what more can one ask for?